We offer dilution buffers optimised for a variety of sequencing machines. Using these buffers can help you save money by reducing your costs. Furthermore, they have been designed to give the best chance of success by offering the possibility of enhanced sequencing reactions.
DNA Sequencing
BetterBase
This is a novel enhancing buffer designed for use with the ABI BigDye® v1.1 and v3.1 sequencing mixes. It is compatible for use with all sequencing machines and replaces either home-made or other commercial dilution buffers. In some instances it has also been shown to improve results from difficult templates.
further information >>
-
citations >>
-
Date Title URL 2010 Mutational screening of VSX1 in keratoconus patients from the European population Link
-
-
further information >>
-
Product Name Unit Size Cat. number Cat. Price Euro Price Data MSDS BetterBuffer 5 x 0.3 ml 3BB-5 £111 €146 
BetterBuffer 10 x 0.3 ml 3BB-10 £214 €280 BetterBuffer 5 x 1.5 ml 3BB1.5-5 £400 €524 BetterBuffer 10 x 1.5 ml 3BB1.5-10 £783 €1,026 BetterBuffer 1 x 25 ml 3BB25 £1,332 €1,745 BetterBuffer Bulk 1 x 250 ml 3BB250 £6,190 €8,113
-
-
citations >>
-
Year Title URL 2011 Phylogenetic Relationships in Pterodroma Petrels Are Obscured by Recent Secondary Contact and Hybridization Link 2010 A Copine family member, Cpne8, is a candidate quantitative trait gene for prion disease incubation time in mouse Link 2010 PRNP Allelic Series From 19 Years of Prion Protein Gene Sequencing at the MRC Prion Unit Link 2010 Species Identification from Genetic Material with Cytochrome b Link 2010 Mixture Detection Applying Mitochondrial DNS SNPs vs Traditional Mitochondrial DNA Sequencing Link 2009 A new technology in mtDNA sequencing: Success rates vs time Link 2009 Crime investigation set on mitochondrial DNA analysis Link 2009 The heritability and genetics of frontotemporal lobar degeneration Link 2009 Shadoo (Sprn) and prion disease incubation time in mice Link 2009 European phylogeography of the common frog (Rana temporaria): routes of postglacial colonization into the British Isles, and evidence for an Irish glacial refugium Link 2009 Patrilocality and recent migrations have little impact on shaping patterns of genetic structure of the armenian population Link 2009 HECTD2 Is Associated with Susceptibility to Mouse and Human Prion Disease Link 2008 A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series Link 2008 Investigation of Mcp1 as a Quantitative Trait Gene for Prion Disease Incubation Time in Mouse Link 2008 Diversity of aminopeptidases, derived from four lepidopteran gene duplications, and polycalins expressed in the midgut of Helicoverpa armigera: Identification of proteins binding the δ-endotoxin, Cry1Ac of Bacillus thuringiensis Link 2007 Latitudinal clines for nucleotide polymorphisms in the Esterase 6 gene of Drosophila melanogaster Link 2007 Somatic mitochondrial DNA mutations in primary and metastatic ovarian cancer Link 2007 Schistosome dystrophin and dystrobrevin proteins contain large insertions Link 2006 Genetic divergence and echolocation call frequency in cryptic species of Hipposideros larvatus s.l. (Chiroptera: Hipposideridae) from the Indo-Malayan region Link 2006 ABCA12 Is the Major Harlequin Ichthyosis Gene Link 2005 Prevalence of Exon 15 BRAF Mutations in Primary Melanoma of the Superficial Spreading, Nodular, Acral, and Lentigo Maligna Subtypes Link 2005 Mutations in ABCA12 Underlie the Severe Congenital Skin Disease Harlequin Ichthyosis Link 2005 Patterns of variability at the major histocompatibility class II alpha locus in Atlantic salmon contrast with those at the class I locus Link 2005 Efficient mispriming during apolipoprotein E genotyping Link 2004 Identification and characterization of a novel mouse prion gene allele Link 2003 No Association with Common Caucasian Genotypes in Exons 8, 13 and 14 of the Human Cytoplasmic Dynein Heavy Chain Gene (DNCHC1) and Familial Motor Neuron Disease Link 2002 Founding Mothers of Jewish Communities: Geographically Separated Jewish Groups Were Independently Founded by Very Few Female Ancestors Link 2002 Scrapie epidemic in a fully PrP-genotyped sheep flock Link
-
-
further information >>
-
Product Name Unit Size Cat. number Cat. Price Euro Price Data MSDS 5x BaseQ 1 ml 3BAQ-1 £16 €24 5x BaseQ 1 x 28 ml 3BAQ28 £440 €577 5x BaseQ Bulk 1 x 233 ml 3BAQ233 £3,595 €4,710
-
BetterBuffer
This is a novel enhancing buffer designed for use with the ABI BigDye® sequencing mixes v1.0 and 3.0. Like BetterBase, it is compatible with all sequencing machines (except MegaBACE) and can be used to reduce costs in the same way. Simply dilute the ABI BigDye®, thereby reducing your consumption and reducing your costs.
5x BaseQ®
This is a straightforward 5x dilution buffer for sequencing reactions and should be used as a direct replacement for ABI dilution buffers. Unlike BetterBase or BetterBuffer it offers no capacity for sequencing enhancement.
